Skin from Diabetics Transformed Into Insulin-Secreting Beta Cells

/ / Blog
Pancreatic Islet Cells  Skin from Diabetics Transformed Into Insulin-Secreting Beta Cells 1x1

Pancreatic Islet Cells

May 11, 2016 02:28 PM By Ali Venosa 

Take some cells from a diabetic’s skin. DE-volve them into a primitive and embryonic state. Manipulate them in the lab into a beta cell.  Throw in some glucose and watch as they produce insulin.  That is what happened in both culture and mouse trials. 

While it may be years or decades until these induced pluripotent stem cells are ready to treat patients; adult stem cells are ready today with a long history of study, therapeutic application, safety and efficacy. 

The most recent attempt to take down diabetes comes from researchers at Washington University School of Medicine in St. Louis and Harvard University, who have managed to change stem cells derived from diabetes patients skin cells into insulin–secreting cells. Patients with Type 1 diabetes lack the ability to create their own insulin, meaning they rely on regular injections of the hormone to control blood sugar.

“In theory, if we could replace the damaged cells in these individuals with new pancreatic beta cells — whose primary function is to store and release insulin to control blood glucose — patients with type 1 diabetes wouldn’t need insulin shots anymore,” said Dr. Jeffery R. Millman, an assistant professor of medicine and biomedical engineering at Washington university and first author of the study, in a press release. “The cells we manufactured sense the presence of glucose and secrete insulin in response. And beta cells do a much better job controlling blood sugar than diabetic patients can.”

Type 1 diabetics cannot create insulin, which is why patients must inject themselves with this hormone throughout the day. Although this new treatment is still being researched, injecting these stem-cell derived insulin-secreting cells into diabetes patients could control blood sugar without the need for medication.

Stem Cell Centers in India, affiliated with Global Stem Cells Group of Miami, Florida, has been in the forefront of regenerative medicine and cellular therapies since 2005. We are a unique network of highly skilled physicians.  Our mission is to bring innovative stem cell therapy to the forefront of medicine and enhance the quality of life for our patients around the world.  To learn more about stem cells and how you can take the first step towards recovery, call +91 9888936107 or write us at info@stemcellinc.in

Story source here and study here

0 Shares